:root{color-scheme:light;--ink:#173c3b;--paper:#f4f5ef;--muted:#546b69;--line:#d5dfd8;--green:#236b60}*{box-sizing:border-box}html{scroll-behavior:smooth}body{margin:0;background:var(--paper);color:var(--ink);font:16px/1.65 system-ui,sans-serif}header{display:flex;align-items:center;gap:28px;padding:24px 5%;border-bottom:1px solid var(--line)}header span{color:var(--muted);font-size:13px}header form{margin-left:auto}.brand{text-decoration:none;font-size:21px;font-weight:700}main{max-width:1200px;margin:56px auto;padding:0 28px}h1{font:clamp(34px,4vw,54px)/1.15 Georgia,serif;max-width:850px;letter-spacing:-1px}h2{font:30px/1.25 Georgia,serif}h3{font-size:18px}a{color:var(--green);text-underline-offset:4px}.eyebrow{font-size:11px;letter-spacing:2px;font-weight:750;color:var(--green)}.intro{font-size:19px;max-width:760px;color:var(--muted)}nav{display:flex;gap:28px;margin:36px 0}.grid{display:grid;grid-template-columns:1.1fr 1fr;gap:22px}.card{background:#fff;border:1px solid var(--line);border-radius:16px;padding:30px;margin:0 0 24px;overflow-wrap:anywhere}.accent{background:#e7eee5}.muted{color:var(--muted);font-size:13px}li{margin-bottom:10px}button{background:var(--green);color:#fff;border:1px solid var(--green);border-radius:8px;padding:12px 20px;font:600 15px system-ui;cursor:pointer}button:hover{background:#174e46}.quiet{background:transparent;color:var(--green);padding:8px 14px}.quiet:hover{color:white}label{display:block;margin:18px 0 5px;font-weight:600}input,textarea{display:block;width:100%;border:1px solid #93aaa4;border-radius:8px;padding:13px;font:inherit;background:white;margin-bottom:18px}input:focus,textarea:focus,button:focus-visible,a:focus-visible,summary:focus-visible{outline:3px solid #c48338;outline-offset:3px}summary{cursor:pointer;color:var(--green);font-weight:600}.notice{background:#fff1d6;border-left:4px solid #ae7428;padding:18px}.login{max-width:530px;margin:70px auto}.login form{margin-top:32px}.tag{display:inline-block;font-size:11px;letter-spacing:.4px;padding:4px 10px;border-radius:20px;background:#edf3ed;margin:0 8px 8px 0}.source,blockquote{white-space:pre-wrap}blockquote{border-left:3px solid #99b6aa;margin:18px 0;padding-left:20px}.answer{margin-top:30px;border-top:1px solid var(--line);padding-top:18px}footer{max-width:1200px;margin:48px auto;padding:24px 28px;color:var(--muted);font-size:13px;border-top:1px solid var(--line)}@media(max-width:760px){.grid{grid-template-columns:1fr}header{gap:12px;flex-wrap:wrap}header span{display:none}main{margin-top:30px;padding:0 18px}.card{padding:22px}nav{gap:18px;flex-wrap:wrap}h1{font-size:37px}}
.language-bar{max-width:1200px;margin:16px auto 0;padding:0 28px;text-align:right}.language-bar button[aria-pressed=true]{background:var(--green);color:white}.check{display:flex;gap:12px;align-items:flex-start;margin:24px 0}.check input{width:auto;margin:7px 0;flex-shrink:0}.profile-tree{margin:0 0 14px}.profile-tree dt{font-weight:650;color:var(--green);margin-top:14px}.profile-tree dd{margin-left:18px;overflow-wrap:anywhere}.profile-tree ul{padding-left:20px}footer p{max-width:750px}

select{display:block;width:100%;border:1px solid #93aaa4;border-radius:8px;padding:13px;font:inherit;background:white;margin-bottom:18px;color:var(--ink)}.portal-nav{flex-wrap:wrap;margin:0 0 36px;padding-bottom:20px;border-bottom:1px solid var(--line)}

.map-controls{display:flex;gap:16px;align-items:flex-end;flex-wrap:wrap}.map-controls>div{flex:1;min-width:180px}.map-controls button{margin-bottom:18px}.map-note{max-width:760px;color:var(--muted)}.map-wrap{overflow-x:auto;padding:16px}.research-map{width:100%;min-width:800px;display:block}.map-edge{fill:none;stroke:#b0c8bf;stroke-width:1.4;opacity:.55}.topic-node{fill:#e9f0e7;stroke:#8bab9f}.topic-node.chosen{fill:#d2e4d4;stroke:#236b60;stroke-width:2}.topic-dot{fill:#236b60}.topic-label{font:600 15px system-ui;fill:#173c3b}.node-count{font:13px system-ui;fill:#546b69}.study-node{fill:#fff;stroke:#c4d5ce}.study-node.selected{stroke:#236b60;stroke-width:3}.trial-dot{fill:#337b8b}.paper-dot{fill:#b0833f}.study-label{font:13px system-ui;fill:#173c3b}.study-id{font:11px system-ui;fill:#546b69}.research-map a:hover rect,.research-map a:focus rect{stroke:#b57b30;stroke-width:3}.report-body{font-size:16px;line-height:1.65;overflow-x:auto}.report-body h1{font-size:30px;letter-spacing:0;line-height:1.25;margin:0 0 20px}.report-body h2{font-size:25px;margin:32px 0 14px;padding-top:16px;border-top:1px solid var(--line)}.report-body h3{font-size:20px;margin:24px 0 10px}.report-body h4{font-size:17px;margin:20px 0 8px}.report-body p{margin:10px 0}.report-body ul,.report-body ol{padding-left:24px}.report-body li{margin-bottom:6px}.report-body table{border-collapse:collapse;width:100%;margin:20px 0}.report-body td,.report-body th{padding:10px;border:1px solid var(--line);text-align:left;vertical-align:top}.report-body th{background:#edf3ed}.report-body hr{border:0;border-top:1px solid var(--line);margin:24px 0}.report-body a{overflow-wrap:anywhere}

.portal-nav{gap:8px;padding:8px;background:#eaf0e7;border:1px solid #d7e1d4;border-radius:18px;box-shadow:0 3px 12px #173c3b05}.portal-nav a{display:flex;align-items:center;justify-content:center;gap:8px;min-height:44px;flex:1 0 auto;padding:10px 14px;border-radius:12px;text-decoration:none;font-size:14px;font-weight:600;transition:background .16s ease,box-shadow .16s ease,transform .16s ease}.portal-nav a:hover{background:#f8faf5;transform:translateY(-1px)}.portal-nav a.active{background:#fff;color:#174e46;box-shadow:0 2px 7px #173c3b12}.portal-nav a.active:before{content:"";width:7px;height:7px;background:#478875;border-radius:50%;flex-shrink:0}button{transition:background .16s ease,transform .16s ease,box-shadow .16s ease}button:active{transform:translateY(1px)}.notice[role=status]{background:#e9f3e9;border-color:#4d8a65;border-radius:0 10px 10px 0}.card{box-shadow:0 3px 16px #173c3b04}main>h1,main>.intro{animation:gentle-arrival .22s ease-out}@keyframes gentle-arrival{from{opacity:.65;transform:translateY(3px)}to{opacity:1;transform:translateY(0)}}@media(prefers-reduced-motion:reduce){html{scroll-behavior:auto}*,*:before,*:after{animation:none!important;transition:none!important}}@media(max-width:760px){.portal-nav{gap:5px}.portal-nav a{flex:1 1 40%;padding:10px 8px;font-size:13px}}

.report-body h3 span,.report-body h4 span{display:inline-block;margin-left:.4em;padding:.1em .45em;border-radius:8px;background:#e9f0e7;font-size:.8em;font-weight:500}
/* Compact navigation and a quiet, non-clinical arrival. */
.site-header{max-width:1200px;margin:auto;padding:12px 28px;gap:16px;border:0;min-height:64px}.brand{font-size:18px;white-space:nowrap}.brand span{font-size:14px;font-weight:400}.header-actions{display:flex;align-items:center;gap:16px;margin-left:auto}.header-actions form{margin:0}.language-switch{display:flex;gap:2px}.language-switch button{border:0;background:transparent;color:var(--muted);padding:8px;min-width:40px;min-height:40px;font-size:12px;border-radius:6px}.language-switch button[aria-pressed=true]{color:var(--ink);text-decoration:underline;text-underline-offset:5px}.language-switch button:hover,.sign-out:hover{background:#e7eee5;color:var(--ink)}.sign-out{background:transparent;color:var(--muted);border:0;padding:8px;font-size:12px;min-height:40px}main{margin-top:4px}.portal-nav{padding:3px;gap:3px;margin-bottom:30px;border-radius:12px;background:transparent;box-shadow:none;border:0;border-bottom:1px solid var(--line)}.portal-nav a{padding:7px 10px;border-radius:8px;font-size:13px;min-height:42px}.portal-nav a.active{background:#e5ede3;box-shadow:none}.welcome{padding:8px 0 18px}.welcome h1{font-size:clamp(34px,4vw,48px);margin:12px 0 16px}.welcome .intro{font-size:18px;max-width:650px;margin:0}.next-step{display:grid;grid-template-columns:1fr 220px;align-items:center;gap:28px;background:#eaf0e5;padding:28px 32px;position:relative;overflow:hidden}.next-step h2{margin:12px 0;font-size:29px}.next-step p:not(.eyebrow){max-width:580px}.button-link{display:inline-flex;align-items:center;gap:20px;background:var(--green);color:white;padding:11px 18px;border-radius:8px;text-decoration:none;font-weight:600}.button-link:hover{background:#174e46}.secondary-link{display:inline-block;margin:14px 0 0 20px;font-size:14px}.welcome-art{position:relative;height:180px;overflow:hidden;border-radius:110px 110px 20px 20px;background:#f6f4df}.sun{position:absolute;width:58px;height:58px;border-radius:50%;background:#e7c887;top:24px;left:82px}.hill{position:absolute;width:300px;height:140px;border-radius:50%;background:#9bb6a1;bottom:-65px;left:0;transform:rotate(-15deg)}.hill-back{background:#c7d5b9;bottom:-28px;left:-90px;transform:rotate(18deg)}.welcome-links{display:grid;grid-template-columns:repeat(3,1fr);gap:22px;margin:0 0 28px}.welcome-links a{text-decoration:none;padding:12px 0}.welcome-links a:hover strong{text-decoration:underline}.welcome-links strong,.welcome-links span{display:block}.welcome-links span{font-size:14px;color:var(--muted);margin-top:4px}.home-tools{border-top:1px solid var(--line);border-bottom:1px solid var(--line);padding:16px 0;margin:8px 0 36px}.home-tools summary{font-size:14px}.home-tools .grid{margin-top:20px}.home-tools .card{margin-bottom:0}#research{scroll-margin-top:20px}
@media(max-width:760px){.site-header{padding:10px 18px;flex-wrap:nowrap}.site-header .brand span{display:none}.header-actions{gap:8px}.portal-nav{flex-wrap:nowrap;overflow-x:auto;justify-content:flex-start;margin-bottom:22px}.portal-nav a{flex:0 0 auto;white-space:nowrap;padding:8px 12px}.next-step{grid-template-columns:1fr;padding:24px}.welcome-art{display:none}.secondary-link{margin:16px 0 0;display:block}.welcome-links{grid-template-columns:1fr;gap:0;margin-bottom:18px}.welcome-links a{border-bottom:1px solid var(--line);padding:14px 0}.welcome .intro{font-size:17px}.welcome{padding-bottom:24px}}
.welcome-links strong span{display:inline;font-size:inherit;color:inherit;margin:0}

.preparation{max-width:820px;margin-inline:auto}.prep-conversation article{background:#edf3ed;border-radius:12px;padding:14px 20px;margin:18px 0}.prep-conversation h3{font-size:14px;margin:0;color:var(--green)}.prep-conversation p{margin:8px 0}.preparation details{margin-top:24px}.preparation textarea{min-height:120px}#resolved-questions>summary{padding:4px 0}#resolved-questions article{margin-top:20px}